Public Release: 1-Aug-2009
Sleep
Dementia induced and blocked in Parkinson's fly model
Researchers at Washington University School of Medicine in St. Louis
have modeled Parkinson's-associated dementia for the first time.
Scientists showed that a single night of sleep loss in genetically
altered fruit flies caused long-lasting disruptions in the flies'
cognitive abilities comparable to aspects of Parkinson's-associated
dementia. They then blocked this effect by feeding the flies large
doses of the spice curcumin.
McDonnell Center for Cellular and Molecular Neurobiology, the American
Parkinson's Association and the National Institutes of Health
Contact: Michael C. Purdy