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Public Release: 23-Mar-2009
237th American Chemical Society National Meeting & Exposition

Tales of the 'Trojan horse drug' and the 'miracle dogs'
Scientists are reporting promising results with a drug called nitrosylcobalamin (NO-Cbl) in battling cancer in dogs without any negative side effects. While it gives profound hope to dog owners, NO-Cbl also points to a powerful new cancer treatment for humans -- one that infiltrates cancer cells like a biological Trojan horse. Their study is scheduled for presentational in March at the 237th National Meeting of the American Chemical Society.
Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society


Public Release: 23-Mar-2009
237th American Chemical Society National Meeting & Exposition

Redefining DNA: Darwin from the atom up
In a dramatic rewrite of the recipe for life, scientists from Florida describe the design of a new type of DNA with 12 chemical letters instead of the usual four. This artificial genetic system already is helping to usher in the era of personalized medicine for millions of patients with HIV, hepatitis and other diseases, they say. Their study is scheduled for presentation in March at the 237th National Meeting of the American Chemical Society.
Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Public Release: 23-Mar-2009
Neurology

Vertigo linked to osteoporosis
People who have osteoporosis are more likely to also have vertigo, according to a study published in the March 24, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology.
Contact: Jenine Anderson
janderson@aan.com
American Academy of Neurology

Public Release: 23-Mar-2009
PLoS Medicine

Comprehensive map of global malaria endemicity -- a key resource for malaria control and elimination
Using data from nearly 8,000 local surveys of malaria parasite infection rates, an international team of researchers has built a global map showing the proportion of the population infected with the parasite Plasmodium falciparum at locations throughout the globe.
Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science

Public Release: 23-Mar-2009
PLoS Medicine

Alcohol-induced flushing is a risk factor for esophageal cancer from alcohol consumption
There is growing evidence, say researchers in this week's PLoS Medicine, that people who experience facial flushing after drinking alcohol are at much higher risk of esophageal cancer from alcohol consumption than those who do not.
Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science

The legendary Himiko may have lived here
Researchers say they have found evidence of what may be an early third-century palace that could have been part of the Yamatai kingdom ruled by Himiko, the legendary queen.
THE ASAHI SHIMBUN
2009/3/23

Public Release: 23-Mar-2009
Journal of Clinical Investigation

Licorice extract blocks colorectal cancer in mice
Although drugs that target the protein COX-2, including aspirin and ibuprofen, prevent the development of intestinal polyps, the precursors of colorectal cancer, they have severe side effects that preclude their routine use for this purpose. However, new research indicates that inhibiting 11-beta-HSD2 (both genetically and using an extract from licorice) blocks COX-2 activity in human and mouse colorectal tumor cells, inhibiting their growth and metastasis in experimental models of colorectal cancer.
American Cancer Society, National Institutes of Health, US Department of Veterans Affairs Contact: Karen Honey
press_releases@the-jci.org
215-573-1850
Journal of Clinical Investigation

Public Release: 23-Mar-2009
Archives of Internal Medicine

Vitamin D supplements associated with reduced fracture risk in older adults
Oral vitamin D supplements at a dose of at least 400 international units per day are associated with a reduced risk of bone fractures in older adults, according to results of a meta-analysis published in the March 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Contact: Heike A. Bischoff-Ferrari, Dr.P.H.
heike.bischoff@usz.ch
JAMA and Archives Journals

Public Release: 23-Mar-2009
Proceedings of the National Academy of Sciences

Social isolation makes strokes more deadly, study finds
New research in mice suggests that social isolation may promote more damaging inflammation in the brain during a stroke. Researchers at Ohio State University found that all the male mice that lived with a female partner survived seven days after a stroke, but only 40 percent of socially isolated animals lived that long.
American Heart Association, NIH/National Institute of Neurological Disorders and Stroke, NIH/National Heart, Lung, and Blood Institute Contact: Kate Karelina
Karelina.1@osu.edu
614-688-4665
Ohio State University

Public Release: 23-Mar-2009
Proceedings of the National Academy of Sciences

Research links evolution of fins and limbs with that of gills
The genetic toolkit animals use to build fins and limbs is the same one that controls the development of part of the gill skeleton in sharks. Also, the skeleton of any animal appendage is probably patterned by the developmental genetic program that regulates the formation of shark gills. This finding is consistent with an old theory, often discounted in textbooks, that fins and (later) limbs evolved from the gills of an extinct vertebrate.
Contact: Greg Borzo
greg.borzo@uchospitals.edu
773-702-0892
University of Chicago Medical Center

Public Release: 23-Mar-2009
Proceedings of the National Academy of Sciences

New research reveals the earliest evidence for corn in the New World
An international team of scientists led by Dolores Piperno, archaeobotanist at the Smithsonian's National Museum of Natural History, and Anthony Ranere, professor of anthropology at Temple University in Philadelphia, have discovered the first direct evidence that indicates maize was domesticated by 8,700 years ago, the earliest date recorded for the crop. The research findings will be published March 23 in the journal Proceedings of the National Academy of Sciences.
Contact: Michele Urie
uriem@si.edu
202-633-2950
Smithsonian

Public Release: 23-Mar-2009
European Journal of Cancer

New data on cancer survival in Europe show more patients are cured
New data and analyses from a long-running study of cancer survival in Europe have shown that the number of people actually cured of cancer -- rather than just surviving for at least five years after diagnosis -- is rising steadily. Reports from the EUROCARE-4 Working Group are published in a special issue of the European Journal of Cancer.
Contact: Emma Mason
wordmason@mac.com
44-771-129-6986
ECCO-the European CanCer Organisation

Synthetic blood from embryos bid
UK scientists plan a major research project to see if synthetic human blood can be made from embryonic stem cells.
Monday, 23 March 2009
Public Release: 23-Mar-2009
Acta Psychiatrica Scandinavica

New research highlights dramatically reduced risk of developing dementia
People with memory problems are less at risk of developing dementia than previously thought, a new study led by the University of Leicester and Nottinghamshire Healthcare NHS Trust reveals.
Contact: Dr. Alex Mitchell
ajm80@le.ac.uk
44-116-225-6218
University of Leicester

Public Release: 23-Mar-2009
Proceedings of the National Academy of Sciences

Listening to pleasant music could help restore vision in stroke patients, suggests study
Patients who have lost part of their visual awareness following a stroke can show an improved ability to see when they are listening to music they like, according to a new study published today in the journal Proceedings of the National Academy of Sciences.
British Academy, Biotechnology and Biological Sciences Research Council, Economic and Social Research Council, Medical Research Council, Stroke Association Contact: Lucy Goodchild
lucy.goodchild@imperial.ac.uk
44-207-594-6702
Imperial College London

Public Release: 23-Mar-2009
Journal of Applied Psychology

Groups share information in workplace, but not the 'right' information
From the operating room to the executive board room, the benefits of working in teams have long been touted. But a new analysis of 22 years of applied psychological research shows that teams tend to discuss information they already know and that "talkier" teams are less effective.
Contact: Audrey Hamilton
ahamilton@apa.org
202-336-5706
American Psychological Association

Public Release: 23-Mar-2009
Stem Cells and Development

Human adult testes cells can become embryonic-like
Using what they say is a relatively simple method, scientists at Georgetown University Medical Center have extracted stem/progenitor cells from testes and have converted them back into pluripotent embryonic-like stem cells. Researchers say that the naïve cells are now potentially capable of morphing into any cell type that a body needs, from brain neurons to pancreatic tissue.
National Institutes of Health Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center

Public Release: 23-Mar-2009
Journal of Neuroscience

Astrocytes help separate man from mouse
A type of brain cell that was long overlooked by researchers embodies one of very few ways in which the human brain differs fundamentally from that of a mouse or rat. Human astrocytes are bigger, faster, and much more complex than those in mice and rats.
G. Harold and Leila Y. Mathers Charitable Foundation, NIH/National Institute of Neurological Disorders and Stroke Contact: Tom Rickey
tom_rickey@urmc.rochester.edu
585-275-7954
University of Rochester Medical Center
Public Release: 23-Mar-2009
Nature

Proteins by design: Penn biochemists create new protein from scratch
Using design and engineering principles learned from nature, a team of biochemists have built -- from scratch -- a completely new type of protein. This protein can transport oxygen, akin to human neuroglobin, a molecule that carries oxygen in the brain and peripheral nervous system. Some day this approach could be used to make artificial blood for use on the battle field or by emergency-care professionals.
US Department of Energy, National Institutes of Health, National Science Foundation Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Public Release: 23-Mar-2009
Proceedings of the National Academy of Sciences

Early agriculture left traces in animal bones
Unraveling the origins of agriculture in different regions around the globe has been a challenge for archeologists. Now researchers writing in the Proceedings of the National Academy of Sciences report finding evidence of early human experiments with grain cultivation in East Asia. They gathered this information from an unlikely source -- dog and pig bones.
Contact: Seth Newsome
snewsome@ciw.edu
202-478-8987
Carnegie Institution

Public Release: 24-Mar-2009
237th American Chemical Society National Meeting & Exposition

Licorice may block effectiveness of drug widely used by transplant patients
Chemists in Taiwan are reporting that an ingredient in licorice -- widely used in various foods and herbal medicines -- appears to block the absorption of cyclosporine, a drug used by transplant patients to prevent organ rejection. This drug interaction could potentially result in illness and death among transplant patients and others taking cyclosporine and licorice together, they caution. Their study is scheduled for presentation in March at the 237th National Meeting of the American Chemical Society.
Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Public Release: 24-Mar-2009
237th American Chemical Society National Meeting & Exposition

New form of destructive terrorist material unlikely, chemists report
Concerns that terrorists could produce a new and particularly dangerous form of the explosive responsible for airport security screening of passengers' shoes and restrictions on liquids in carryon baggage are unfounded, a group of scientists is reporting. Their study, which demonstrates that a new form of destructive terrorist material is unlikely, is scheduled for presentation at the 237th National Meeting of the American Chemical Society.
Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Public Release: 24-Mar-2009
Anesthesiology

Mayo researchers find link between anesthesia exposure and learning disabilities in children
Mayo Clinic researchers have found that children who require multiple surgeries under anesthesia during their first three years of life are at higher risk of developing learning disabilities later.
Contact: Marie Zhuikov
newsbureau@mayo.edu
507-284-5005
Mayo Clinic

Public Release: 24-Mar-2009
Clinical Cancer Research

NYU study finds new risk factor for melanoma in younger women
Researchers may have found a more potent risk factor for melanoma than blistering sunburns, freckling, or family history of the deadly skin disease. In a new study, scientists at NYU Langone Medical Center report that a genetic variation leads to a nearly four-fold increase of melanoma in women under the age of 50. The new study was released online March 24, 2009, in the journal Clinical Cancer Research, and will be published in the April 1, 2009, issue of the journal.
Marc Jacobs Campaign to Support Melanoma Research, NIH/National Cancer Institute Contact: Lorinda Klein
lorindaann.klein@nyumc.org
212-404-3533
NYU Langone Medical Center / New York University School of Medicine

Public Release: 24-Mar-2009
Neurogastroenterology and Motility

Herbal medicines for treatment of gastrointestinal disease
Herbal medicines could benefit patients suffering from gastrointestinal (GI) motility disorders that cannot be treated using conventional drug therapy. In a study published in Neurogastroenterology and Motility, researchers reviewed data on Japanese herbal medicines and found them to be effective in reducing the symptoms of GI disorders such as functional dyspepsia, constipation and postoperative ileus.
Contact: Jennifer Beal
wbnewseurope@wiley.com
44-124-377-0633
Wiley-Blackwell

Really?
The Claim: Fish Oil Supplements Can Contain Mercury
Could fish oil capsules contain the harmful pollutant found in some species of fish?
By ANAHAD O'CONNOR
Oozing Through Texas Soil, a Team of Amoebas Billions Strong
A field of genetically identical amoebas in Texas raises the possibility that cells might organize on much larger scales than once thought.
By CAROL KAESUK YOON
Botox Frees Muscles for Stroke Patients in the Know
The drug used for reducing wrinkles is also being used to relax muscles stiffened by a stroke.
* Health Guide: Stroke »
By DONALD G. McNEIL Jr.

Public Release: 24-Mar-2009
New England Journal of Medicine

New study set to change how critically ill patients are treated
The current practice of intensively lowering blood glucose in critically ill patients increases the risk of death by 10 percent. Results of the largest trial of intensive glucose lowering in critically ill patients published today in the New England Journal of Medicine indicate that international clinical guidelines need urgent review.
Contact: Emma Orpilla
eorpilla@george.org.au
61-299-934-500
Research Australia

Public Release: 24-Mar-2009
Proceedings of the National Academy of Sciences

Researchers studying hearing loss find auditory regions of the brain convert to the sense of touch
Virginia Commonwealth University School of Medicine researchers have discovered that adult animals with hearing loss actually re-route the sense of touch into the hearing parts of the brain.
National Institutes of Health Contact: Sathya Achia Abraham
sbachia@vcu.edu
804-827-0890
Virginia Commonwealth University

Public Release: 24-Mar-2009
Nature Geoscience

Deep-sea rocks point to early oxygen on Earth
Red jasper cored from layers 3.46 billion years old suggests that not only did the oceans contain abundant oxygen then, but that the atmosphere was as oxygen rich as it is today, according to geologists.
NASA Astrobiology Institute Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Public Release: 24-Mar-2009
Alarming new data shows TB-HIV co-infection a bigger threat
The World Health Organization released staggering new data about the threat of tuberculosis and the toll it takes on people with HIV/AIDS today, in recognition of World TB Day.
Contact: Deirde Shesgreen
dshesgreen@idsociety.org
703-740-4954
Infectious Diseases Society of America


Briny pools 'may exist on Mars'
Pools of salty water might be able to exist just below the surface of Mars, planetary scientists tell a major US conference.
Probe ends historic Mars mission
Q&A: Liquid water on Mars
24 March 2009

Five classic examples of gene evolution
Find out why humans have better colour perception than dogs, how light-refracting eye proteins came about, and how a bacteria manages to munch on waste chemicals from nylon manufacture
16:56 24 March 2009
How speeding cancer growth offers hope of cure
Certain cancer therapies may make tumours grow more aggressively depending on the dose given, new research shows, which paradoxically could help discover a cure
11:16 25 March 2009
Desire to amputate healthy limbs shows up in brain scans
Scans of people with the "body integrity identity disorder" show an abnormal response in areas that form a mental body map
14:02 25 March 2009
Beneficial Alzheimer's gene can be perilous in pairs
If you inherit one copy of a particular gene mutation it seems to protect you from Alzheimer's – but inherit a copy from both parents and you may be in trouble...
IN BRIEF:  15:41 25 March 2009
Germany's stone age cannibalism
Tens of thousands of ancient human bones found in Germany suggest that victims were not killed just to satisfy hunger
Guardian UK
Public Release: 25-Mar-2009
Journal of American Chemical Society
New drug agent knocks out multiple enzymes in cancer pathway
A team of 24 researchers from the US, Europe, Taiwan and Japan and led by University of Illinois scientists has engineered a new anti-cancer agent that is about 200 times more active in killing tumor cells than similar drugs used in recent clinical trials. The study appears this week in the Journal of the American Chemical Society.
Contact: Diana Yates
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign

Public Release: 25-Mar-2009
24th Annual EAU Congress
Nature

A new approach to prostate cancer detection
US researcher Dr. Chris Beecher from the University of Michigan gave a well attended lecture about sarcosine at the 24th Annual EAU Congress in Stockholm, Sweden. Dr Beecher is a colleague of lead author Dr. Arun Sreekumar. The research looked at more than 1,000 small molecules in tissues associated with prostate cancer. These findings suggest that not only is sarcosine a marker of cancer aggressiveness, it also has a role in endowing a cancer with malignant properties.
Contact: Lindy Brouwer
l.brouwer@uroweb.org
European Association of Urology

Public Release: 25-Mar-2009
Lab on a Chip
A fast magnetic fix for sepsis?
An innovative new device created by researcher's at Children's Hospital Boston uses magnetism to quickly pull disease pathogens out of an infected bloodstream. The device could become a first-line defense for blood infections like sepsis, which causes over 200,000 deaths in the US per year.
Center for Integration of Medicine and Innovative Technology, National Nanotechnology Infrastructure Network
Contact: James Newton
james.newton@childrens.harvard.edu
617-919-3110
Children's Hospital Boston

Public Release: 26-Mar-2009
American Journal of Cardiology
Mending a broken heart: Study offers closer look at 'broken heart syndrome'
Researchers from the Miriam Hospital created a registry of 70 patients with the medical phenomenon known as "broken heart syndrome."
Contact: Jessica Collins Grimes
jgrimes2@lifespan.org
401-793-7484
Lifespan

Artificial cartilage performs better than the real thing
Synthetic bone joints could outperform the natural materials they replace, thanks to tiny brushes made of plastic
18:00 26 March 2009
Ironware piece unearthed from Turkey found to be oldest steel
The Hindu
Public Release: 26-Mar-2009
British Medical Journal

Drinking very hot tea can increase the risk of throat cancer
People are advised to wait a few minutes before drinking a cup of freshly boiled tea today as a new study, published on bmj.com, finds that drinking very hot tea (70 degrees C or more) can increase the risk of cancer of the esophagus, the muscular tube that carries food from the throat to the stomach.
Contact: Emma Dickinson
edickinson@bmj.com
44-207-383-6529
BMJ-British Medical Journal

Public Release: 26-Mar-2009
Population and Development Review

Do Americans have an identity crisis when it comes to race and ethnicity?
Say goodbye to Italian-Americans and German-Americans and say hello to Vietnamese-Americans, Salvadoran-Americans and a bunch of other hyphenated Americans. The way people identify themselves in the United States is changing, and the way the federal census classifies them by race or ethnicity isn't painting a clear portrait of America, according to new research.
NIH/National Institute of Child Health and Human Development Contact: Joel Schwarz
joels@u.washington.edu
206-543-2580
University of Washington

Public Release: 30-Mar-2009
Personality and Social Psychology Bulletin

Study: Embrace the 'Dwight Schrutes' in your office for better performance
Nobody wants to share a cubicle with a new hire like Dwight Schrute. The beet-farming volunteer sheriff's deputy/paper salesman creates many awkward moments because of his differences with co-workers on NBC's "The Office." But according to new research co-authored by a Brigham Young University business professor, better decisions come from teams that include a "socially distinct newcomer." That's psychology-speak for someone who is different enough to bump other team members out of their comfort zones.
Contact: Michael Smart
michael_smart@byu.edu
801-422-7320
Brigham Young University









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